Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. Sontag E, Hladik C, Montgomery L, Luangpirom A, Mudrak I, Ogris E, White CL 3rd. J Neuropathol Exp Neurol. 2004 Oct;63(10):1080-91. PubMed PMID: 15535135.