Eduardo Perez, Ph.D. Chief Scientific Office

Eduardo Perez, Ph.D. Chief Scientific Office

Eduardo Perez attended the Nerium International Regional Event held in Mexico City, Mexico. He discussed the science behind SIG1273, our 2nd generation isoprenylcysteine (IPC) cosmetic functional ingredient (CFI). At the cellular level, SIG1273 has to the ability to inhibit the production of pro-inflammatory cytokines and prevent the oxidative damage associated with chronic inflammation and stress. SIG1273 has been clinically proven to be safe and effective in protecting the skin from inflammatory and microbial invaders. It was also designed to possess anti-aging and anti-microbial properties.

Properties:

  1. Anti-aging benefits
    • promotes wound healing
    • protect against UVA damage
    • Protect against oxidative stress
    • Anti-wrinkle (reduces collagenase production, which protects collagen)
  2. Anti-inflammatory properties
    • Protects against chemical induced pro-inflammatory cytokine release
    • Protects against bacterial induced (TLR2) pro-inflammatory cytokine release
    • Protects against metal induced (TLR4) induced pro-inflammatory cytokine release
    • Protects against T-cell induced pro-inflammatory cytokine release
    • Protects against UV induced pro-inflammatory cytokine release
    • Reduces COX expression
  3. Blocks neutrophil infiltration
  4. Possesses anti-microbial activity against P. acnes and S. pyogenes
  5. Clinically proven to possess anti-acne activity

Follow the link to learn more about Sig-1273 http://signumdermalogix.com/sig1273

Video of Sig1273 https://www.youtube.com/watch?v=AGugn0ic6SU (1 min in duration)