Signum’s science and IP involve key lipid chemistries and the signaling loci they modulate. The company’s research and development effort build upon two-decades of basic research at the Princeton University laboratory of Professor Jeffry B. Stock, co-founder of Signum Biosciences. This work on G-protein-mediated signaling and protein phosphorylation regulation demonstrated that long-chain lipid chemistries could be used to balance global G-protein-mediated signaling and protein kinase/phosphorylation networks.Copy of Copy of Untitled

Lipids have a wide variety of important functions within cells, including sub cellular partitioning, protein trafficking, membrane anchoring, and first and second messenger signaling. Lipid biology is a major research target of the post genomic revolution, and the comprehensive analysis of lipid molecules -- lipidomics -- is increasingly recognized as crucial to understanding cellular physiology and pathology.

SIG-990 (DMT200/DMT210)

protecting you from harsh elements.

SIG-990 (aka DMT200/DMT210) reduces the inflammation signals that respond to external triggers such as UV rays, dryness, trauma, stress, and even extreme changes in temperature. The reduction of these inflammatory signals helps eliminate the redness and inflamed lesions associated with Rosacea, leaving you with brighter, healthier skin.

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Our science is the brains
behind your grey matter.

EHT® is a naturally-occurring, proprietary molecule to support brain health.†

Derived from coffee, EHT is already a part of many people’s daily diet, but now on a more concentrated level. The second most traded commodity in the world supports better brain health.

† These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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fighting inflammation to fight aging.

The SIG-1273® molecule has the ability to decrease the body’s chronic inflammation fighters, which attack the site of inflammation, but can also do extensive damage to the surrounding healthy cells as well. It helps keep the body from reaching the inflammation-fighting point of diminishing returns. SIG-1273® also reduces the breakdown of collagen, which is essential for our skin to continue looking supple and healthy.

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hydrated skin for a younger look.

As we age, our skin tends to get thinner, drier and weaker, losing the supple firmness associated with younger skin. SIG-1191™ utilizes Aquaporin 3 (AQP3) to increase hydration in the base layer of our skin. Hydration helps to repair dry skin, heal wounds, and hydrate while reducing the appearance of dark spots and puffiness under the eyes by breaking up the heme stagnation that causes them to appear originally. Even as we age, our skin can remain firm, hydrated and strong with the right care.

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guarding against UVB induced DNA damage and inflammation.

Arazine™ can help keep UVB rays from penetrating the skin and causing damage on a microscopic level. This kind of damage will trigger inflammatory responses that could attack the healthy skin cells around the source of inflammation.

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