Rohto Pharmaceuticals

Rohto is a Japan-based company that manufactures and sells a wide range of products including skincare, eye care, and oral medicines. Headquartered in Osaka, Rohto has 20 subsidiaries and five associated companies, giving them broad reach in the Japanese markets. We jointly develop new applications and products with Rohto’s RVK (Research Village Kyoto) facility. Our partnership includes a semi-exclusive license for Arazine™ in Japan only. In addition Rohto has made a significant investment into Signum and have a seat on our Board of Directors. We will continue to contribute to Rohto’s strategic goals, while enhancing the commercial, business development and market focus of Signum’s technologies.

We have partnered with HydraFacial to develop a new booster serum for the HydraFacial Treatment. This new Neck and Decollete Booster Serum is the first of its kind and is HydraFacial’s only neck and decollete booster. Formulated with AGSE and Hyvia, this booster serum helps to reduce inflammation, increase hydration, strengthen the skin barrier, and balance skin tone.

HydraFacial

We have partnered with Chicmax Kans, a domestic Chinese cosmetic company developing novel cosmetic products for the Chinese market. Together we have developed the PP2A line of products that focuses specifically on activating PP2A to improve skin health.

Chicmax Shanghai

We have partnered with Elizabeth Arden, Inc., on an exclusive global license for the cosmetic functional ingredient Arazine™ (N-acetyl-S-farnesyl-cysteine) as well as developing new screening methodologies to measure the anti-oxidant potential of other product ingredients. Arazine™ was recently launched as a key ingredient in Elizabeth Arden’s Prevage® Anti-aging + Intensive Repair Daily Serum product. We look forward to collaborating with Elizabeth Arden’s efforts in producing innovative, high-quality skin care products supported with robust scientific data.

Elizabeth Arden

Neora International

Neora International, LLC, headquartered in Addison, Texas, is a relationship marketing company that markets breakthrough products validated by science. Since its August 2011 launch, Neora has reached record-breaking sales and earned industry accolades while building millions of consumer fans along the way. Led by an award-winning executive team with more than 200 years of collective industry experience, Neora is committed to developing and distributing anti-aging products that are rooted in real science, produce real results, and improve consumers’ lives. Our partnership will contribute to Neora International’s strategic goals and future products to be developed utilizing Signum’s technologies and research capabilities. We look forward to a productive, long-term relationship.